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Clinical Trials/Medical Research

Microscope with laboratory glassware

Clinical Trials/Medical Research

Clinical trials are patient studies that test new treatments and therapies, which are an essential part of advancing medicine. All clinical trials are approved and closely monitored by the IRB (Institutional Review Board). Doylestown Health is actively involved in a variety of clinical trial research programs.

Clinical Trials Available

Why are Clinical Trials Important?

Clinical trials must take place before new research treatments or devices can be made available to the public. Trials are designed to help determine the safety and effectiveness of new treatments and additional possibilities for patients facing certain medical conditions.

For clinical trials to be successful, we rely on patient volunteers who meet specific criteria to participate in these studies. The ultimate goal of a clinical trial is to obtain knowledge that can then be used to improve the health and well-being of various patient populations.

Should I Participate in a Clinical Trial?

Choosing to participate in a clinical trial is an important personal decision. To make a fully informed decision, before deciding whether to participate in a study, it is often helpful to talk to your health care provider, family members, or friends. After you have identified trial options, the next step is to contact the study research staff and ask questions about specific trials.

Many guidelines are in place for patient volunteers, by Doylestown Health, the sponsoring company, and at the Federal level (FDA).

Where Can I Find Out More Information on a Specific Clinical Trial?

If you are interested in participating in a clinical trial you may call Doylestown Health's Medical Research department at 215.345.2119 and speak with one of our research coordinators to answer any questions you may have regarding a clinical trial or review trials available.

Institutional Review Board (IRB)

Institution Review Boards are established to ensure the rights and welfare of people who choose to participate in clinical trials both before and during their trial participation. The primary function of the IRB is to guarantee adherence to all federal, state, local, and institutional regulations concerning the protection of all human subjects when testing investigational drugs or medical devices. These impartial review panels assess the risks and benefits of each study trial to minimize and fairly disclose risk to study participants.

Doylestown Health is committed to being a foremost clinical research center where standards of care are elevated both now and in the future.

Infectious Disease Clinical Trials

These clinical trials are coordinated by the Doylestown Health Medical Research Department: 215.345.2119.

Upcoming Trials - Not Yet Enrolling:

Influenza A – DIAMOND

  • To evaluate the Safety and Efficacy of a new oral drug in combination with standard of care treatment in non-hospitalized patients with Influenza A who are at risk of developing complications

Influenza A - SAPPHIRE

  • To evaluate the Safety and Efficacy of a new JNJ oral drug in combination with our standard of care in hospitalized patients with influenza A.

Nephrology Clinical Trials

These clinical trials are coordinated by the Doylestown Health Medical Research Department: 215.345.2119.

Active Trials - Open to Enrollment:

Anemia Related to Non-dialysis-dependent Chronic Kidney Disease - Akebia Therapeutics

  • Efficacy and safety study to Evaluate Vadadustat for the maintenance treatment of anemia in Subjects with Non-dialysis-dependent chronic kidney disease
  • Compares an investigational oral medication vs the standard injectable medication

Anemia in Chronic Kidney Disease - MONOFER

  • A study is comparing Venofer IV iron (standard) vs Monofer IV iron (investigational)
  • Monofer IV Iron is a one-time infusion of iron over 20 minutes vs Venofer IV Iron which is an hour and a half infusion which is usually given five times over the course of three to four weeks

Neurology Clinical Trials

These clinical trials are coordinated by the Doylestown Health Medical Research Department: 215.345.2119.

Upcoming Trials - Not Yet Enrolling:

Acute Ischemic Stroke - QUEST-KETA

  • Quelling of Excitotoxicity in Acute Stroke with Ketamine (QUEST-KETA) trial will investigate the efficacy and side effects of IV Ketamine to reduce neuroexcitotoxicity, and thus provide neuroprotection in patients diagnosed with acute ischemic stroke.

Pulmonary Clinical Trials

These clinical trials are coordinated by the Doylestown Health Medical Research Department: 215.345.2119.

Active Trials - Open to Enrollment:

Non-Cystic Fibrosis Bronchiectasis - The Willow Study

  • Study will evaluate the efficacy and tolerability of an oral inti-inflammatory medication vs. placebo
  • Non-Cystic Fibrosis Bronchiectasis is a progressive disorder associated with airway dilation and bronchial wall thickening.

For more information about Doylestown Health's open trials visit the U.S. National Institutes of Health's Clinical Trials database.

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