Cancer Clinical Trials and Research Programs

Doylestown Health's Cancer Institute is a member of the Eastern Cooperative Oncology Group (ECOG), one of the largest clinical cancer research organizations in the United States, and conducts clinical trials in all types of adult cancers. ECOG is funded by the National Cancer Institute (NCI), part of the National Institutes of Health (NIH).

Doylestown Health conducts research and clinical trials in collaboration with Jefferson’s Sidney Kimmel Cancer Network. Our cancer care team is proud to offer local patients the most current opportunities and the convenience of participating in these vitally important cancer research programs close to home.


Jennifer Perri, RN, BSN, OCN
Clinical Trial Nurse Coordinator

Doylestown Health is currently enrolling patients in the following approved oncology protocols:

Early Stage Breast Cancer


  • Phase III Randomized Trial
  • Breast Cancer Weight Loss Study (BWEL Study)
  • Evaluating the Role of Weight Loss in Adjuvant Treatment of Overweight and Obese Women with Early Breast Cancer


  • Phase III Randomized Trial
  • Adjuvant Hormonal Therapy with or without one year of Everolimus in patients with high-risk, hormone receptor-positive and HER2/Neu negative breast cancer.

Recurrent Breast Cancer


  • Phase III Randomized Trial
  • Endocrine Therapy plus Entinostat or Placebo in patients with Hormone Receptor-Positive Advanced Breast Cancer


  • Phase II Randomized Trial
  • Tamoxifen or Z-Endoxifen in Postmenopausal Women with Metastatic Estrogen Receptor Positive, HER2 Negative Breast Cancer

Lung Cancer

Alchemist: 2-Step Study   

Learn more at the National Cancer Institute web site

Prostate Cancer

Newly Metastatic Hormone Sensitive: S1216

  • Phase III Randomized Trial Comparing Androgen Deprivation Therapy + TAK-700 with Androgen Deprivation Therapy + Bicalutamide in Patients with Newly Diagnosed Metastatic Hormone Sensitive Prostate Cancer

For more information about open cancer trials at Doylestown Health, go to the U.S. National Institutes of Health’s web site